Comparison of Metformin and Simvastatin Administration in Women With Polycystic Ovary Syndrome Before Intra-Cytoplasmic Sperm Injection Cycle: A Prospective, Randomized, Clinical Trial Study

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comparison of metformin and simvastatin administration in women with polycystic ovary syndrome before intra-cytoplasmic sperm injection cycle: a prospective, randomized, clinical trial study

conclusions simvastatin effectively improved hyperandrogenism signs and symptoms in patients with pco, but this effect as a pretreatment regiment was not more expressive than metformin in icsi cycle outcome. patients and methods in this prospective, double blind, randomized clinical trial the efficacy of these drugs was evaluated in 40 women with pco syndrome (20 patients in each group; a: simv...

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Comparison of Metformin and Simvastatin Administration in Women With Polycystic Ovary Syndrome Before Intra-Cytoplasmic Sperm Injection Cycle: A Prospective, Randomized, Clinical Trial Study

BACKGROUND Drugs administration as a pretreatment regiment before ICSI cycle in PCOs patients could enhance the success rate. OBJECTIVES The aim of this study was to compare the effectiveness of metformin with Simvastatin in patients with polycystic ovary syndrome (PCOs) candidates for intra-cytoplasmic sperm injection (ICSI) before starting the cycle. PATIENTS AND METHODS In this prospecti...

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Metformin treatment before IVF/ICSI in women with polycystic ovary syndrome; a prospective, randomized, double blind study.

BACKGROUND Our aim was to investigate the effect of pre-treatment with metformin in women with polycystic ovary syndrome (PCOS) scheduled for IVF stimulation. METHODS Seventy-three oligo/amenorrhoeic women with polycystic ovaries and at least one of the following criteria: hyperandrogenaemia, elevated LH/FSH ratio, hyperinsulinism, decreased SHBG levels or hirsutism, were studied. Normal weig...

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Effects of Melatonin Administration on Chemical Pregnancy Rates of Polycystic Ovary Syndrome Patients Undergoing Intrauterine Insemination: A Randomized Clinical Trial

Objective Background: Oxidative stress as a potential cause of poor oocyte quality can influence female reproduction. This study aimed to investigate the effects of melatonin on chemical pregnancy rates of a significant number of polycystic ovary syndrome (PCOS) patients undergoing intrauterine insemination (IUI). MaterialsAndMethods Materials and Methods: In this randomized double-blinded clin...

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Comparison of In Vitro Fertilization/Intracytoplasmic Sperm Injection Cycle Outcome in Patients with and without Polycystic Ovary Syndrome: A Modified Poisson Regression Model

Objective Polycystic ovary syndrome is a frequent condition in women of reproductive age with prevalence rate of 5-10%. This study purposed to determine the relationship between polycystic ovary syndrome and the outcome of assisted reproductive treatment (ART) cycle in Tehran, Iran. MaterialsAndMethods In this historical cohort study, 996 infertile women were included in the study between Janua...

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ژورنال

عنوان ژورنال: Iranian Red Crescent Medical Journal

سال: 2015

ISSN: 2074-1804,2074-1812

DOI: 10.5812/ircmj.20082